CAS: 1355612-71-3

Aldose reductase-IN-1

Aldose reductase-IN-1 is a potent and selective inhibitor, which is a synthetic small molecule with a specific mode of action aimed at targeting the aldose reductase enzyme. Originating from pharmacological research, this compound is designed to interfere directly with the enzyme's activity. Aldose reductase-IN-1 functions by binding to the active site of aldose reductase, thus preventing the reduction of glucose to sorbitol, a crucial step in the polyol pathway. The primary application of Aldose reductase-IN-1 is in the study of diabetes complications, particularly those involving the secondary impacts of elevated blood sugar levels. By inhibiting aldose reductase, this compound aids in exploring therapeutic avenues for mitigating the development of diabetic neuropathy, retinopathy, and nephropathy. Beyond diabetes research, the specificity of Aldose reductase-IN-1 makes it a valuable tool for investigating the broader implications of polyol pathway dysregulation in various biological contexts.

Aldose reductase-IN-1 (AT-001, Caficrestat) is a highly potent inhibitor of aldose reductase.Cost-effective and quality-assured.