CAS: 1357570-21-8

Applications A metabolite of Ramipril (R111000). This compound is not stable in an aqueous solution.

Ramipril-acyl-β-D-glucuronide

Ramipril acyl-b-D-glucuronide is a glycosylated prodrug that is the active form of ramipril, an ACE inhibitor. It is metabolized in the liver to ramipril and excreted in the urine. Ramipril acyl-b-D-glucuronide has been shown to have an increased bioavailability and a longer half-life than ramipril due to its glycosylation. The synthesis of this drug has been modified by methylation, fluorination, and saccharide modification. This compound is also available as a custom synthesis for research purposes with high purity.