
CAS: 1357576-48-7
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Found 5 products.
AZD4320
CAS:AZD4320 inhibits BCL2/BCLxL; IC50: KPUM-MS3=26nM, KPUM-UH1=17nM, STR-428=170nM.Formula:C45H48ClF3N4O7S3Purity:98.13% - 99.71%Color and Shape:SolidMolecular weight:945.53Ref: TM-T14376
1mg77.00€5mg145.00€10mg198.00€25mg411.00€50mg682.00€100mg1,198.00€1mL*10mM (DMSO)207.00€AZD4320
CAS:AZD4320 is a molecule that binds to the CDK4/CDK6 complex, which controls the cell cycle. AZD4320 has been shown to induce apoptosis in cancer cells by triggering mitochondrial membrane depolarization and long-term treatment of chronic lymphocytic leukemia. AZD4320 also inhibits the proliferation of leukemic cells by binding to CDK4/CDK6. This agent has potential as an anti-leukemic drug because it can be used in combination with monoclonal antibodies and thrombocytopenia drugs.Formula:C45H48ClF3N4O7S3Purity:Min. 95%Molecular weight:945.5 g/mol