The chemical substance known as (5Z)-5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-2,4-thiazolidinedione, with CAS number 136401-69-9, is a thiazolidinedione derivative, which is a class of compounds known for their role in pharmacology, particularly in the treatment of diabetes. This compound features a thiazolidinedione core, characterized by a five-membered ring containing sulfur and nitrogen, which is linked to a phenyl group substituted with an ethoxy and pyridine moiety. The presence of the ethyl group on the pyridine ring enhances its lipophilicity, potentially influencing its biological activity and pharmacokinetics. Thiazolidinediones are known to act as agonists of peroxisome proliferator-activated receptors (PPARs), which play a crucial role in glucose and lipid metabolism. The specific structural features of this compound suggest potential applications in metabolic disorders, but detailed studies would be necessary to elucidate its efficacy, safety, and mechanism of action in biological systems.

(5Z)-5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-2,4-thiazolidinedione

136401-69-9: (5Z)-5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methylidene)-1,3-thiazolidine-2,4-dione, (5Z)-5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-2,4-thiazolidinedione, (Z)-5-{4-[2-(5-Ethylpyridin-2-Yl)Ethoxy]Benzylidene}-1,3-Thiazolidine-2,4-Dione, 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-, (5Z)-, 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-, (Z)-

Pioglitazone EP impurity B

Pioglitazone EP Impurity B

5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-2,4-thiazolidinedione-D4

Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure

CAS 136401-69-9: (5Z)-5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-2,4-thiazolidinedione

Pioglitazone EP impurity B

Ref: ST-EA-CP-P7002

Pioglitazone EP Impurity B

Ref: 4Z-P-1018

5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-2,4-thiazolidinedione-D4

Ref: TR-E924937

(5Z)-Didehydro Pioglitazone ((Z)-5-{4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzylidene}thiazolidine-2,4-dione)

Ref: 45-1A07390