2-Chloro-6-methoxyquinoline is an organic compound characterized by its quinoline structure, which consists of a fused benzene and pyridine ring. The presence of a chlorine atom at the second position and a methoxy group at the sixth position of the quinoline ring significantly influences its chemical properties and reactivity. This compound typically appears as a yellow to brown solid and is sparingly soluble in water but more soluble in organic solvents such as ethanol and dichloromethane. It exhibits potential biological activity, making it of interest in medicinal chemistry and pharmaceutical research. The chlorine substituent can enhance its lipophilicity, while the methoxy group may contribute to its electron-donating properties. Additionally, 2-chloro-6-methoxyquinoline can participate in various chemical reactions, including nucleophilic substitutions and electrophilic aromatic substitutions, due to the presence of both electron-withdrawing and electron-donating groups. Its unique structure and properties make it a valuable compound for further studies in organic synthesis and drug development.

2-Chloro-6-methoxyquinoline

13676-02-3: Quinoline, 2-chloro-6-methoxy-, 2-Chloro-6-methoxyquinoline

2-Chloro-6-methoxyquinoline is a molecule that has been prepared synthetically by the palladium-catalyzed coupling of an organometallic reagent and a quinoxaline. The metal chelation of 2-chloro-6-methoxyquinoline to the quinoline moiety is a kinase selectivity for protein phosphatases, which are enzymes that regulate cellular signaling at the level of protein phosphorylation. Pharmacokinetic parameters have been determined for 2-chloro-6-methoxyquinoline in rats, which showed it had good oral absorption and was metabolized by oxidation at the methoxy group.

CAS 13676-02-3: 2-Chloro-6-methoxyquinoline

2-Chloro-6-methoxyquinoline

Ref: 3D-FC43603

2-Chloro-6-methoxyquinoline

Ref: 54-OR307500

Quinoline, 2-chloro-6-methoxy-

Ref: IN-DA0012BO

2-Chloro-6-methoxyquinoline

Ref: 10-F092338