CAS: 1372605-11-2

6-Hydroxy monopropylheptylphthalate (6-HMPA) is a metabolite of the drug dibutyl phthalate. It has been detected in human urine and can be used as a biomarker for exposure to this compound. The presence of 6-HMPA in urine is correlated with logistic regression models and kinetic data. The metabolism of dibutyl phthalate is primarily mediated by cytochrome P450 2C19, which converts it to 6-HMPA. This compound can be monitored using a variety of analytical methods, including gas chromatography/mass spectrometry, liquid chromatography/mass spectrometry, and high performance liquid chromatography.

Applications 6-OH-Monopropylheptylphthalate is a phthalate metabolite originating from a DPHP (B523500) used in plasticizers to improve chemical and physical properties. References Kasper-Sonnenberg, M. et al.: Int. J. Hyg. Env. Health, 215, 373 (2012); Koch, H. et al.: Int. J. Hyg. Env. Health, 214, 188 (2011);