CAS: 1374516-07-0

TUG-891 is a G protein-coupled receptor expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids.

TUG-891 is a selective agonist for the G-protein coupled receptor 120 (GPR120), which is derived from complex organic synthesis processes. Its mode of action involves the targeted activation of GPR120, a receptor deeply involved in the regulation of inflammation and metabolic pathways, particularly in the context of fatty acid signaling. The compound modulates downstream signaling cascades, leading to anti-inflammatory and insulin-sensitizing effects through GPR120 activation. In scientific research, TUG-891 serves as a vital tool for exploring the physiological and pathological roles of GPR120. Its applications are primarily centered around studies of metabolic disorders, such as type 2 diabetes, obesity, and inflammatory diseases, providing insights into novel therapeutic avenues. By elucidating GPR120’s involvement in these processes, TUG-891 helps advance the understanding of metabolic regulation and the development of potential pharmacological interventions.

TUG-891