3-Chloro-4-fluorophenyl isothiocyanate is an organic compound characterized by the presence of both a chloro and a fluoro substituent on a phenyl ring, along with an isothiocyanate functional group. Its molecular structure features a phenyl ring with a chlorine atom at the meta position and a fluorine atom at the para position relative to the isothiocyanate group. This compound is typically a yellow to brown solid at room temperature and is known for its reactivity, particularly in nucleophilic substitution reactions due to the presence of the isothiocyanate group. It is often used in organic synthesis and may serve as a building block in the development of pharmaceuticals or agrochemicals. The compound's reactivity can also make it useful in various chemical applications, including as a reagent in the synthesis of other functionalized compounds. Safety precautions should be observed when handling this substance, as it may pose health risks due to its reactive nature and potential toxicity.

3-Chloro-4-fluorophenyl isothiocyanate

137724-66-4: Art-Chem-Bb B006856, Akos B006856, 2-Chloro-1-Fluoro-4-Isothiocyanato-Benzene, Timtec-Bb Sbb003683, Benzene, 2-chloro-1-fluoro-4-isothiocyanato-, 3-Chloro-4-fluorophenylisothiocyanate

Benzene, 2-chloro-1-fluoro-4-isothiocyanato-

3-Chloro-4-fluorophenol isothiocyanate is a nucleophilic reagent that reacts with electron-deficient molecules such as thiourea. The nucleophilic attack of the electron-deficient molecule by the electron transfer of 3-chloro-4-fluorophenol isothiocyanate leads to the formation of a covalent bond. The interaction between 3-chloro-4-fluorophenol isothiocyanate and thiourea was studied experimentally, and it was found that the frequency of this reaction depends on the distance between them. The atomic orbital of 3-chloro-4-fluorophenol isothiocyanate interacts with the molecular orbital of thiourea, forming a new molecular orbital which stabilizes the reactants.

CAS 137724-66-4: 3-Chloro-4-fluorophenyl isothiocyanate

Benzene, 2-chloro-1-fluoro-4-isothiocyanato-

Ref: IN-DA0013S8

3-Chloro-4-fluorophenyl isothiocyanate

Ref: 54-PC1886M

3-Chloro-4-fluorophenol isothiocyanate

Ref: 3D-FC71905

3-Chloro-4-fluorophenyl isothiocyanate

Ref: 10-F008759