CAS 137848-28-3: (R)-Nobin

(R)-2’-Amino-[1,1’-Binaphthalen]-2-Ol

(R)-(+)-2-Amino-2'-hydroxy-1,1'-binaphthyl is an enantiopure, stereoselective compound that is used in the synthesis of picolinic acid and other biologically active compounds. The nitrogen atoms in this molecule are said to be chiral centers. The asymmetric synthesis of (R)-(+)-2-Amino-2'-hydroxy-1,1'-binaphthyl has been achieved through a reaction mechanism involving trifluoromethanesulfonic acid as a catalyst. It is also used as an antimicrobial agent against bacteria and fungi. (R)-(+)-2-Amino-2'-hydroxy-1,1'-binaphthyl chelates metal ions such as calcium ions and magnesium ions by hydrogen bonding interactions with their amino groups. It also inhibits the activity of certain enzymes that regulate cell growth and differentiation, such as estrogen receptors.