CAS: 1380548-02-6

SR10067 is a drug candidate that inhibits the activity of sirtuin 1, which is a protein that regulates cellular metabolism. SR10067 has been shown to increase mitochondrial biogenesis and enhance cardiac function in animals with heart disease. This drug also regulates muscle mass and reduces the risk of age-related muscle loss. The spectrometric data obtained from SR10067’s interaction with mitochondria indicate that this drug may be effective for treating age-related diseases such as cancer and neurodegenerative disorders.

SR10067 is a potent, selective and brain penetrant agonist of Rev-Erbβ(IC50 = 160 nM) and Rev-Erbα(IC50 = 170 nM) with anxiolytic activity.

SR10067