Osteostatin, identified by the CAS number 138949-73-2, is a peptide that plays a significant role in bone metabolism and regulation. It is primarily known for its involvement in inhibiting osteoclastogenesis, which is the process of bone resorption by osteoclasts, thereby contributing to bone density maintenance. Osteostatin is derived from the precursor protein osteopontin and exhibits a complex structure that includes various amino acids, which are crucial for its biological activity. The peptide is typically characterized by its ability to bind to specific receptors on cell surfaces, influencing signaling pathways that regulate bone remodeling. Additionally, osteostatin has been studied for its potential therapeutic applications in conditions such as osteoporosis and other metabolic bone diseases. Its stability, solubility, and interaction with other biomolecules are important factors that determine its efficacy in biological systems. Overall, osteostatin represents a key component in the intricate balance of bone formation and resorption, highlighting its significance in skeletal health.

Osteostatin

138949-73-2: H-Thr-Arg-Ser-Ala-Trp-OH, Thr-Arg-Ser-Ala-Trp

Please enquire for more information about Osteostatin (1-5) (human, bovine, dog, horse, mouse, rabbit, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Osteostatin (1-5) (human, bovine, dog, horse, mouse, rabbit, rat) trifluoroacetate salt

The pentapeptide TRSAW, a highly conserved sequence within the pTH-related protein, is a potent inhibitor of osteoclastic bone resorption in vitro (EC₅₀ = 10⁻¹⁵ M).

CAS 138949-73-2: Osteostatin

Osteostatin (1-5) (human, bovine, dog, horse, mouse, rabbit, rat) trifluoroacetate salt

Ref: 3D-FO110332

Osteostatin (1-5) (human, bovine, dog, horse, mouse, rabbit, rat)

Ref: 01-4019104