CAS 1404-64-4: (+)-Sparsomycin
Formula:C13H19N3O5S2
InChI:InChI=1S/C13H19N3O5S2/c1-8-10(12(19)16-13(20)14-8)3-4-11(18)15-9(5-17)6-23(21)7-22-2/h3-4,9,17H,5-7H2,1-2H3,(H,15,18)(H2,14,16,19,20)/b4-3+/t9-,23+/m0/s1
InChI key:InChIKey=XKLZIVIOZDNKEQ-CLQLPEFOSA-N
SMILES:C(=C/C(N[C@H](CS(CSC)=O)CO)=O)\C1=C(C)NC(=O)NC1=O
Synonyms:- (2E)-3-(2,4-dihydroxy-6-methylpyrimidin-5-yl)-N-[(2S)-1-hydroxy-3-{[(methylsulfanyl)methyl]sulfinyl}propan-2-yl]prop-2-enamide
- (2E)-N-[(1S)-1-(Hydroxymethyl)-2-[(R)-[(methylthio)methyl]sulfinyl]ethyl]-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidinyl)-2-propenamide
- (2E)-N-[(2S)-1-hydroxy-3-{[(methylsulfanyl)methyl]sulfinyl}propan-2-yl]-3-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)prop-2-enamide
- (2E)-N-[2-hydroxy-1-({[(methylsulfanyl)methyl]sulfinyl}methyl)ethyl]-3-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)prop-2-enamide
- 2-Propenamide, N-[(1S)-1-(hydroxymethyl)-2-[(R)-[(methylthio)methyl]sulfinyl]ethyl]-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidinyl)-, (2E)-
- 2-Propenamide, N-[1-(hydroxymethyl)-2-[[(methylthio)methyl]sulfinyl]ethyl]-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidinyl)-, [R-[R*,S*-(E)]]-
- 2-propenamide, 3-(2,4-dihydroxy-6-methyl-5-pyrimidinyl)-N-[(1S)-2-hydroxy-1-[[[(methylthio)methyl]sulfinyl]methyl]ethyl]-, (2E)-
- 5-Pyrimidineacrylamide, 1,2,3,4-tetrahydro-N-[1-(hydroxymethyl)-2-[[(methylthio)methyl]sulfinyl]ethyl]-6-methyl-2,4-dioxo-, (E)-(1S)-
- NSC 059729
- NSC 59729
- U 19183
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Found 5 products.
Sparsomycin
CAS:Sparsomycin is an antibiotic compound, which is a secondary metabolite isolated from Streptomyces species. Its mode of action involves the inhibition of protein synthesis by targeting the large subunit of the ribosome, specifically binding to the 50S subunit in bacterial ribosomes and the 60S subunit in eukaryotic ribosomes. This binding interferes with peptide bond formation, thereby disrupting the translational process essential for protein synthesis. Sparsomycin's unique mechanism has made it a valuable tool in molecular biology and biochemical studies, particularly for examining the intricacies of ribosomal function and protein synthesis. Although not widely used clinically due to its broad-spectrum activity that can affect both prokaryotic and eukaryotic cells, its role in research for understanding ribosomal antibiotics and serving as a pharmacological probe remains significant. By studying its interaction with the ribosome, scientists can gain insights into the development of new antibiotics and targets for antibacterial treatment, as well as enhance the understanding of drug-ribosome interactions.Formula:C13H19N3O5S2Purity:Min. 95%Molecular weight:361.4 g/molSparsomycin
CAS:Sparsomycin is an antitumor antibiotic. It also inhibits protein synthesis in the 70S and 80S ribosomal systems.Formula:C13H19N3O5S2Purity:98%Color and Shape:SolidMolecular weight:361.44
