4-(Trifluoromethyl)-DL-phenylalanine, with the CAS number 14091-16-8, is an amino acid derivative characterized by the presence of a trifluoromethyl group attached to the phenyl ring of phenylalanine. This modification significantly influences its chemical properties, including increased lipophilicity and altered reactivity compared to standard phenylalanine. The trifluoromethyl group is known for its electron-withdrawing effects, which can impact the compound's interactions in biological systems and its overall stability. As a zwitterionic compound, it exhibits both acidic and basic properties, allowing it to participate in various biochemical reactions. This substance is of interest in medicinal chemistry and drug design due to its potential applications in developing pharmaceuticals that target specific biological pathways. Additionally, its unique structural features may contribute to its role in influencing protein folding and function. Overall, 4-(Trifluoromethyl)-DL-phenylalanine serves as a valuable compound for research in both organic chemistry and biochemistry.

4-(Trifluoromethyl)-DL-phenylalanine

14091-16-8: 2-Amino-3-(4-Trifluoromethyl-Phenyl)-Propionic Acid, 2-Amino-3-[4-(Trifluoromethyl)Phenyl]Propanoic Acid, DL-4-Trifluoromethyl-Phe-OH, 4-Trifluoromethylphenylalanine,  4-Trifluoromethyl-DL-phenylalanine

4-(Trifluoromethyl)-DL-phenylalanine (4-TFMPP) is a fluorinated analogue of phenylalanine. It is a macrocyclic inhibitor that binds to and inhibits the enzyme ketoreductase, which is involved in the synthesis of ketone bodies in the liver. 4-TFMPP has been shown to be effective against cardiovascular disorders, infectious diseases, and cancer cells. 4-TFMPP also inhibits acyltransferases and phenylephrine hydroxylase, which are enzymes that regulate lipid metabolism and neurotransmitter levels in the brain.

CAS 14091-16-8: 4-(Trifluoromethyl)-DL-phenylalanine

4-(Trifluoromethyl)-DL-phenylalanine

Ref: 3D-FT82788

4-(Trifluoromethyl)-dl-phenylalanine

Ref: 10-F007985

4-(Trifluoromethyl)-DL-phenylalanine

Ref: 54-PC4562

2-Amino-3-(4-(trifluoromethyl)phenyl)propanoic acid

Ref: IN-DA007LGY