CAS: 1414455-03-0

Guajadial B acts as a Top1 catalytic inhibitor and delays Top1 poison-mediated DNA damage.

Guajadial B is a naturally occurring compound, which is a triterpenoid sourced from plants in the Myrtaceae family, notably Psidium guajava. This compound has attracted research interest due to its multi-faceted mode of action, involving modulation of various biological pathways that may contribute to its anticancer, anti-inflammatory, and antimicrobial properties. The mode of action typically involves interaction with cellular targets that regulate apoptosis, cell proliferation, and immune responses. Guajadial B's potential applications are primarily found in the biomedical field, where it serves as a lead compound for the development of novel therapeutic agents. Its anticancer properties make it a candidate for oncological research, where it is studied for its ability to induce cell death in cancer cells and inhibit tumor growth. Additionally, its anti-inflammatory and antimicrobial activities are of interest for developing treatments for inflammatory diseases and infections. Ongoing research into the mechanisms of Guajadial B continues to expand its potential uses and applications in drug discovery and development.