CAS 141524-74-5: 4-Bromo-1-methyl-1H-imidazole-5-carboxaldehyde

4-Bromo-1-methyl-1H-imidazole-5-carbaldehyde (4BMICA) is a prodrug that has been shown to inhibit the growth of cancer cells by binding to the active site residues of the protein guanine nucleotide exchange factor (GEF) mcf-7. It is an analog of etoposide, which can act as a competitive inhibitor for the GEF. 4BMICA binds to and inhibits the activity of epidermal growth factor receptor (EGFR). This drug has been shown to have anti-inflammatory properties, as it inhibits lipid peroxidation and protein tyrosine nitration in rat liver microsomes.