CAS 143-67-9: Vinblastine sulfate
Formula:C46H58N4O9·H2O4S
InChI:InChI=1S/C46H58N4O9.H2O4S/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7;1-5(2,3)4/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3;(H2,1,2,3,4)/t28-,37-,38+,39+,42-,43+,44+,45-,46-;/m0./s1
InChI key:InChIKey=KDQAABAKXDWYSZ-PNYVAJAMSA-N
SMILES:S(=O)(=O)(O)O.C(C)[C@@]12[C@]3([C@@]4([C@]([C@](C(OC)=O)(O)[C@@H]1OC(C)=O)(N(C)C=5C4=CC(=C(OC)C5)[C@]6(C(OC)=O)C7=C(C=8C(N7)=CC=CC8)CC[N@@]9C[C@](C6)(C[C@](CC)(O)C9)[H])[H])CCN3CC=C2)[H]
Synonyms:- (2Alpha,2'Beta,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine
- (2Alpha,2'Beta,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine Sulfate
- (2Alpha,2'Beta,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine Sulfate (1:1)
- (2Alpha,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine
- (2Alpha,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine Sulfate
- 1H-Indolizino[8,1-cd]carbazole, vincaleukoblastine deriv.
- 29060Le
- 2H-3,7-Methanoazacycloundecino[5,4-b]indole, vincaleukoblastine deriv.
- Alkaban-AQ
- NSC 49842
- VLB monosulfate
- See more synonyms
Sort by
Found 15 products.
VINBLASTINE SULFATE CRS
CAS:VINBLASTINE SULFATE CRSFormula:C46H60N4O13SColor and Shape:PowderMolecular weight:909.0526Vinblastine Sulphate-d3
CAS:Controlled ProductApplications Vinblastine Sulphate-d3 is labelled salt of Vinblastine, which is an antitumor alkaloid isolated from periwinkle, Vinca rosea Linn., Apocynaceae; inhibits microtubule assembly. References Lu, C., et al.: Cancer Research, 39, 3575 (1979), Gobbi, P.G., et al.: J. Clin. Oncol., 14, 527 (1996), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs. Excip., 21, 611 (1992),Formula:C46H55D3N4O9·xH2SO4Color and Shape:NeatMolecular weight:813.999808Vinblastine Sulfate
CAS:Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoiFormula:C46H58N4O9·H2SO4Color and Shape:White Light Yellow PowderMolecular weight:908.38776Vinblastine sulfate
CAS:Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).Formula:C46H58N4O9·H2SO4Purity:97.81% - 99.38%Color and Shape:White PowderMolecular weight:909.06vincaleukoblastine,sulfate(1:1)
CAS:Formula:C46H60N4O13SPurity:97%Color and Shape:SolidMolecular weight:909.0526Vinblastine sulfate, 96.0-102.0%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C46H60N4O13SPurity:96.0-102.0%Color and Shape:White to light yellow, Crystalline powderMolecular weight:909.06Vinblastine sulfate
CAS:Formula:C46H60N4O13SPurity:≥ 97.0%Color and Shape:White to off-white powderMolecular weight:909.06Vinblastine sulfate, 96%
CAS:Controlled ProductVinblastine sulfate, 96%, is a chemotherapeutic agent, which is a semi-synthetic derivative of natural alkaloids extracted from the Madagascar periwinkle plant, Catharanthus roseus. This compound functions through the disruption of microtubule formation by binding to tubulin, effectively inhibiting mitosis. By preventing the assembly of microtubules, vinblastine sulfate interferes with the metaphase stage of cell division, leading to cell cycle arrest and subsequent apoptosis of rapidly dividing cancer cells. Vinblastine sulfate is primarily utilized in the treatment of various malignancies, including Hodgkin's lymphoma, non-Hodgkin's lymphoma, breast cancer, and testicular cancer. Its efficacy lies in selectively targeting and interrupting the proliferative processes of cancerous cells, making it a crucial component in combination chemotherapy regimens. Researchers and clinicians appreciate its ability to enhance therapeutic outcomes when used alongside other chemotherapeutic agents, optimizing cancer treatment protocols. The knowledge of vinblastine's mechanism of action has also spurred further research into microtubule inhibitors, broadening the horizon of potential cancer therapies.Formula:C46H60N4O13SPurity:Min. 96 Area-%Color and Shape:PowderMolecular weight:909.05 g/molVinblastine sulfate
CAS:Controlled ProductDisrupts microtubule assembly; anti-cancer agentFormula:C46H60N4O13SPurity:Min. 80 Area-%Color and Shape:White PowderMolecular weight:909.05 g/molVinblastine Sulfate (Vincristine EP Impurity H Sulfate)
CAS:Formula:C46H58N4O9·H2O4SColor and Shape:White To Off-White SolidMolecular weight:810.99 98.08Vinblastine-d6 Sulfate
CAS:Controlled ProductFormula:C46D6H52N4O9·H2SO4Color and Shape:NeatMolecular weight:915.09
