CAS: 1430806-04-4

PF 05089771 is a ligand that has been shown to activate the G-protein coupled receptor, GPRC6A. It has also been shown to inhibit the activity of protein kinase A and protein phosphatase 1D. PF 05089771 is a research tool for studying the ion channels and peptides that are involved in cell biology and cell signaling. This compound is an antibody inhibitor and can be used as a research tool for studying protein interactions.

PF 05089771 tosylate

PF-05089771 inhibits Nav1.7 channels (IC50: 11-33 nM), selective over Nav1.1-1.6/1.8, Ca+, K+ channels, TRPV1; 1000x affinity for half-inactivated state.