CAS: 143130-94-3

(Z)-Azoxystrobin is a strobilurin fungicide, which is a synthetic derivative of naturally occurring antifungal compounds produced by fungi such as *Strobilurus tenacellus*. Its mode of action involves the inhibition of mitochondrial respiration in target fungi, specifically by binding to the Qo site of the cytochrome bc1 complex. This disrupts electron transport in the mitochondria, leading to the cessation of ATP production and subsequent cell death. The primary uses and applications of (Z)-Azoxystrobin are in agriculture, where it is utilized to protect a wide range of crops from fungal pathogens. It is highly effective against diseases such as powdery mildew, downy mildew, and various leaf spot diseases. Its systemic activity allows it to penetrate plant tissues, providing both preventive and curative effects. This fungicide is valued for its broad-spectrum activity, relatively low toxicity to non-target organisms, and ability to improve plant health by reducing disease-related stresses. Researchers continue to study its efficacy, resistance management strategies, and environmental impact to optimize safe and sustainable use in crop protection.

Applications Strobilurin fungicide; inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1. Agricultural fungicide. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Smalling, K., et al.: Environ. Toxicol. Chem., 29, 2593 (2010), Lu, X., et al.: Phytopathol., 100, 1162 (2010), Schafer, R., et al.: Environ. Sci. Technol., 45, 1665 (2011),