Cefamandole is a semisynthetic cephalosporin antibiotic that belongs to the beta-lactam class of antibiotics. It is primarily used to treat a variety of bacterial infections, particularly those caused by Gram-positive and some Gram-negative bacteria. Cefamandole exhibits a broad spectrum of activity and is effective against organisms such as Staphylococcus aureus and Escherichia coli. The compound is characterized by its beta-lactam ring, which is essential for its antibacterial activity, and a side chain that enhances its pharmacological properties. Cefamandole is typically administered parenterally, as it is not well absorbed from the gastrointestinal tract. Its pharmacokinetics involve distribution throughout body tissues, with a relatively short half-life, necessitating multiple doses for effective treatment. Common side effects may include allergic reactions, gastrointestinal disturbances, and alterations in blood coagulation. As with other antibiotics, the emergence of resistance is a concern, making susceptibility testing important for effective clinical use.

cefamandole

144125-09-7: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(hydroxyphenylacetyl)amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, [6R-[6α,7β(S*)]]-

CAS 144125-09-7: cefamandole

Cefamandole Impurity 17

Ref: 4Z-C-162024

Cefamandole Impurity 17

Ref: ST-EA-CP-C488003