CAS 144424-80-6: Lup-20(29)-ene-3,28-diol,3-[(2E)-3-(4-hydroxyphenyl)-2-propenoate], (3b)-

3-o-(E)-p-Coumaroylbetulin is a naturally occurring triterpenoid compound, which is a derivative of betulin. This product is isolated from plant sources, particularly known from species of the Betulaceae family, such as birch trees. The mode of action of 3-o-(E)-p-Coumaroylbetulin is primarily associated with its ability to interact with cellular pathways, influencing anti-inflammatory and antioxidant activities. Its molecular structure allows it to engage in various biochemical interactions, potentially modulating signal transduction pathways involved in inflammation and cellular oxidative stress. Research into the uses and applications of 3-o-(E)-p-Coumaroylbetulin reveals its promise in medicinal and pharmacological contexts. Specifically, this compound has been studied for its potential anti-cancer properties, owing to its capability to induce apoptosis in certain cancer cell lines. Additionally, its anti-inflammatory properties suggest applications in managing conditions characterized by excessive inflammation. The exploration of its pharmaceutical potential continues to be an active area of scientific investigation.

3-β-O-trans-p-coumaroylbetulinol has anti-angiogenic effect, it possesses significant anti-proliferative activity with 66.7% inhibition at 100uM.