(-)-O-Desmethyltramadol hydrochloride is a chemical compound that is a derivative of tramadol, an analgesic medication used to treat moderate to moderately severe pain. This substance is characterized by its chiral nature, with the "(-)" indicating its specific stereoisomeric form. It primarily acts as a mu-opioid receptor agonist, contributing to its analgesic properties, while also inhibiting the reuptake of norepinephrine and serotonin, which can enhance its pain-relieving effects. The hydrochloride salt form improves its solubility and stability, making it suitable for pharmaceutical formulations. In terms of safety and regulatory status, like other opioids, it may have potential for abuse and dependence, necessitating careful handling and prescription. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are influenced by its chemical structure, which affects its interaction with biological systems. Overall, (-)-O-desmethyltramadol hydrochloride is significant in the context of pain management and requires further research to fully understand its therapeutic potential and safety profile.

(-)-O-DESMETHYLTRAMADOL, HYDROCHLORIDE

144830-15-9: (-)-2-[(Dimethylamino)Methyl]-1-(3-Hydroxyphenyl)Cyclohexanol, Hcl, (-)-(1S,2S)-O-Desmethyl Tramadol Hcl, ODT, 2-[(Dimethylamino)methyl]-1-(3-hydroxyphenyl) cyclohexanol hydrochloride

(-)-O-Desmethyl Tramadol (1.0mg/ml in Acetonitrile)

Applications A optically active metabolite of Tramadol.
References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)


CAS 144830-15-9: (-)-O-DESMETHYLTRAMADOL, HYDROCHLORIDE

(-)-O-Desmethyl Tramadol (1.0mg/ml in Acetonitrile)

Ref: TR-KIT4100

(-)-O-Desmethyl Tramadol

Ref: TR-D294745