CAS 1449-05-4: 18α-Glycyrrhetinic acid
Formula:C30H46O4
InChI:InChI=1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21+,22+,23-,26-,27+,28+,29-,30-/m1/s1
InChI key:InChIKey=MPDGHEJMBKOTSU-PMTKVOBESA-N
SMILES:C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](O)CC3)[H])(C(=O)C=C4[C@@]2(C)CC[C@]5(C)[C@@]4(C[C@](C(O)=O)(C)CC5)[H])[H]
Synonyms:- (3Beta)-3-Hydroxy-11-Oxoolean-12-En-30-Oate
- (3Beta)-3-Hydroxy-11-Oxoolean-12-En-30-Oic Acid
- (3Beta,18Alpha)-3-Hydroxy-11-Oxoolean-12-En-30-Oic Acid
- (3beta,18alpha,20beta)-3-Hydroxy-11-oxoolean-12-en-29-oic acid
- (3β,18α,20β)-3-Hydroxy-11-oxoolean-12-en-29-oic acid
- 18-Isoglycyrrhetinic acid
- 18-alpha-Olean-12-en-30-oic acid, 3-beta-hydroxy-11-oxo-
- 18-β Glycyrrhetinic Acid
- 18α-Glycyrrhetic acid
- 18α-Glycyrrhetinic acid
- 18α-Olean-12-en-30-oic acid, 3β-hydroxy-11-oxo-
- See more synonyms
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Found 12 products.
18α-Glycyrrhetinic acid
CAS:18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.Formula:C30H46O4Purity:98.54% - 99.68%Color and Shape:SolidMolecular weight:470.6818α-glycyrrhetinic acid
CAS:Carboxylic acid with additional oxygen functionsFormula:C30H46O4Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:470.7Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,18α,20β)-
CAS:Formula:C30H46O4Color and Shape:SolidMolecular weight:470.683818-alpha-Glycyrrhetinic acid
CAS:Controlled Product18-alpha-Glycyrrhetinic acid is an anti-inflammatory compound, which is a triterpenoid derivative sourced from the root of the licorice plant, Glycyrrhiza glabra. It exhibits its mode of action by inhibiting the activity of the enzyme 11-beta-hydroxysteroid dehydrogenase type 2 (11β-HSD2), which converts active glucocorticoids to their inactive forms. This inhibition leads to increased local concentrations of glucocorticoids, thereby enhancing their anti-inflammatory effects at the application site. The compound is extensively utilized in the field of dermatology due to its potent anti-inflammatory and skin-calming properties. It is commonly applied in the formulation of topical creams and ointments aimed at treating various skin conditions such as eczema, psoriasis, and dermatitis. Additionally, it has been investigated for its potential in aiding wound healing and reducing signs of skin irritation. Owing to its natural origin and multifunctional therapeutic profile, 18-alpha-Glycyrrhetinic acid continues to be a subject of interest for further scientific research and development in pharmacology.Formula:C30H46O4Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:470.68 g/mol18Alpha-Glycyrrhetinic Acid
CAS:Controlled ProductApplications 18α-Glycyrrhetinic Acid rapidly and reversibly blocks gap junction intercellular communication (GJIC). References Guo, Y., et. al.: Am. J. Phys.: 276, L1018 (1999)Formula:C30H46O4Color and Shape:NeatMolecular weight:470.6818-α-Glycyrrhetinic acid
CAS:18-alpha-Glycyrrhetinic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C30H46O4Purity:(HPLC) ≥99%Color and Shape:PowderMolecular weight:470.7
