4-(1-Adamantyl)aniline, with the CAS number 1459-48-9, is an organic compound characterized by the presence of an adamantyl group attached to an aniline structure. This compound features a rigid, cage-like adamantane moiety, which contributes to its unique physical and chemical properties. It typically appears as a solid at room temperature and is known for its relatively high melting point compared to simpler anilines due to the bulky adamantyl group. The presence of the amino group (-NH2) in the aniline part of the molecule allows for potential hydrogen bonding, influencing its solubility and reactivity. 4-(1-Adamantyl)aniline can participate in various chemical reactions, including electrophilic aromatic substitution and nucleophilic reactions, making it a valuable intermediate in organic synthesis. Its unique structure may also impart interesting biological activities, which can be explored in medicinal chemistry. However, specific safety and handling guidelines should be followed, as with all chemical substances, to mitigate any potential hazards associated with its use.

4-(1-Adamantyl)Aniline

1459-48-9: 4-(Tricyclo[3.3.1.1~3,7~]Dec-1-Yl)Aniline, 4-(Adamantan-1-yl)aniline, 4-Adamantan-1-yl-phenylamine, Benzenamine, 4-tricyclo[3.3.1.1~3,7~]dec-1-yl-

4-(1-ADAMANTYL)ANILINE

4-(1-Adamantyl)aniline

4-(1-Adamantyl)aniline is a monomer with electron-deficient properties. It can be synthesized from 1-adamantanol and trifluoroacetic acid, followed by hydrolysis to remove the trifluoromethyl group. 4-(1-Adamantyl)aniline has been shown to have high cytotoxicity against tumor cells in vitro. This compound also inhibits the production of necrosis factor, an inflammatory cytokine that plays an important role in many pathological processes, such as septic shock and acute respiratory distress syndrome.

CAS 1459-48-9: 4-(1-Adamantyl)Aniline

4-(1-ADAMANTYL)ANILINE

Ref: IN-DA00APGD

4-(1-Adamantyl)aniline

Ref: TR-A208253

4-(1-Adamantyl)aniline

Ref: 3D-FA67613

4-(Adamantan-1-yl)aniline

Ref: 54-OR81434

4-(Adamantan-1-yl)aniline

Ref: 10-F634409