Leupeptin trifluoroacetate salt is a synthetic compound derived from the natural peptide leupeptin, which is known for its ability to inhibit serine and cysteine proteases. This compound is often utilized in biochemical and molecular biology research due to its effectiveness in preventing protein degradation during cell lysis and extraction processes. The trifluoroacetate salt form enhances its solubility in organic solvents and aqueous solutions, making it easier to handle in laboratory settings. Leupeptin is particularly valuable in studies involving proteolytic enzymes, as it helps maintain protein integrity and stability. The compound is typically characterized by its white to off-white crystalline appearance and is soluble in water and various organic solvents. It is important to handle leupeptin trifluoroacetate salt with care, as it may pose health risks if ingested or inhaled, and appropriate safety measures should be taken during its use in research applications.

LEUPEPTIN TRIFLUOROACETATE SALT

147385-61-3: Acetyl-Leu-Leu-Arg-Al Trifluoroacetate Salt, Leupeptin Trifluoroacetate From*Microbia L Source, Leupeptintrifluoroacetatesalt90+%, (2S)-2-[[(2S)-2-acetamido-4-methyl-pentanoyl]amino]-N-[(1S)-1-formyl-4-guanidino-butyl]-4-methyl-pentanamide, 2,2,2-Trifluoroacetic Acid

Leupeptin is an enzyme inhibitor that is used to study nicotinic acetylcholine receptors. It has been shown to be reactive in plasma glucose assays and to have a phenotype that is similar to that of type 2 diabetes mellitus in animals. Leupeptin inhibits the activity of viruses such as herpes simplex virus and pseudorabies virus by binding to the nicotinic acetylcholine receptor on the surface of cells. Leupeptin also inhibits autophagy, which may be due to its ability to inhibit the synthesis of proteins necessary for this process. The drug has been shown to act as a morphogenetic protein and trigger differentiation of bovine embryonic stem cells into cardiomyocytes. Leupeptin also binds with high affinity to the hydrophobic pocket on protein kinase C-α (PKCα) and blocks its activation, leading to apoptosis or cell death.

CAS 147385-61-3: LEUPEPTIN TRIFLUOROACETATE SALT

Leupeptin Trifluoroacetate

Ref: 3D-FL29629

Leupeptin trifluoroacetate salt

Ref: 54-BIMI1322

Leupeptin trifluoroacetate salt

Ref: 7W-GK8303