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CAS 1474034-05-3: N-(2-Cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoropropanamide

Formula:C33H44F2N2O3
InChI:InChI=1S/C33H44F2N2O3/c1-27(2)11-13-33(37-26(40)32(8,34)35)14-12-31(7)24(20(33)17-27)21(38)15-23-29(5)16-19(18-36)25(39)28(3,4)22(29)9-10-30(23,31)6/h15-16,20,22,24H,9-14,17H2,1-8H3,(H,37,40)/t20-,22-,24-,29-,30+,31+,33-/m0/s1
InChI key:InChIKey=RJCWBNBKOKFWNY-IDPLTSGASA-N
SMILES:N(C(C(C)(F)F)=O)[C@]12[C@]([C@@]3([C@@](C)(CC1)[C@@]4(C)C(=CC3=O)[C@]5(C)[C@@](CC4)(C(C)(C)C(=O)C(C#N)=C5)[H])[H])(CC(C)(C)CC2)[H]
Synonyms:
  • Skyclarys
  • N-(2-Cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoropropanamide
  • Omaveloxolone
  • Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-
  • RTA 408
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Found 7 products.
  • Omaveloxolone

    CAS:
    Omaveloxolone
    Purity:≥98%
    Molecular weight:554.71g/mol

    Ref: 54-BUP07563

    1mg
    61.00€
    2mg
    85.00€
    5mg
    135.00€
    10mg
    185.00€
    25mg
    306.00€
    50mg
    504.00€
  • N-(2-Cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoropropanamide

    CAS:
    N-(2-Cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoropropanamide is a creatine kinase inhibitor that can be used for the treatment of myocardial infarct, as well as for other diseases such as nephrology and dialysis. It has been shown to inhibit viral replication by preventing the mitochondrial membrane potential from being disrupted. N-(2-Cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2 difluoropropanamide also inhibits granule neurons in the brain. This drug may be a potential drug target for the treatment of Alzheimer's disease and glomerular filtration rate.
    Formula:C33H44F2N2O3
    Purity:Min. 95%
    Molecular weight:554.71 g/mol

    Ref: 3D-FC101357

    1mg
    Discontinued
    2mg
    Discontinued
    5mg
    Discontinued
    10mg
    Discontinued
    25mg
    Discontinued
    Discontinued product
  • RTA 408-d3

    Controlled Product
    CAS:
    Formula:C33D3H41F2N2O3
    Color and Shape:Neat
    Molecular weight:557.729

    Ref: TR-R700992

    50mg
    12,048.00€
  • N-((4As,6Ar,6Bs,8Ar,12As,14Ar,14Bs)-11-Cyano-2,2,6A,6B,9,9,12A-Heptamethyl-10,14-Dioxo-1,3,4,5,6,6A,6B,7,8,8A,9,10,12A,14,14A,14B-Hexadecahydropicen-4A(2H)-Yl)-2,2-Difluoropropanamide

    CAS:
    N-((4As,6Ar,6Bs,8Ar,12As,14Ar,14Bs)-11-Cyano-2,2,6A,6B,9,9,12A-Heptamethyl-10,14-Dioxo-1,3,4,5,6,6A,6B,7,8,8A,9,10,12A,14,14A,14B-Hexadecahydropicen-4A(2H)-Yl)-2,2-Difluoropropanamide
    Molecular weight:554.71g/mol

    Ref: 54-PC108762

    1g
    1,852.00€
    100mg
    355.00€
    250mg
    593.00€
  • Omaveloxolone

    CAS:
    Purity:99.40%
    Molecular weight:554.723

    Ref: 10-F979543

    25mg
    171.00€
  • Omaveloxolone

    CAS:
    Omaveloxolone (RTA-408) (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.
    Formula:C33H44F2N2O3
    Purity:98.7% - 99.1%
    Color and Shape:Solid
    Molecular weight:554.71

    Ref: TM-T6919

    1mg
    46.00€
    2mg
    59.00€
    5mg
    87.00€
    10mg
    119.00€
    25mg
    210.00€
    50mg
    354.00€
    100mg
    512.00€
    500mg
    1,093.00€
    1mL*10mM (DMSO)
    107.00€
  • Nrf1-activator-1

    CAS:
    Formula:C33H44F2N2O3
    Purity:99%
    Color and Shape:Solid
    Molecular weight:554.7108663999999

    Ref: IN-DA00ABL1

    5mg
    71.00€
    10mg
    96.00€
    25mg
    150.00€
    50mg
    181.00€
    100mg
    305.00€
    250mg
    688.00€