CAS 147650-70-2: (S)-Piperazine-2-carboxylic acid

(2S)-Piperazine-2-carboxylic acid

(S)-Piperazine-2-carboxylic acid is a synthetic amide and a member of the piperazine class of compounds. It is used to manufacture the drug clonidine, which is used for treating high blood pressure and other conditions. (S)-Piperazine-2-carboxylic acid has been shown to be an active substance in the synthesis of glutamate by enzymatic hydrolysis. This reaction is optimal at pH 6.5, but it can also occur at pH 2.0 with the addition of hydrochloric acid. The activity of this compound has been studied in mutant strains of Xenopus oocytes. In control experiments, (S)-piperazine-2-carboxylic acid was found to be orally active and showed kinetic properties that were dependent on muscle type and concentration.