CAS 147663-01-2: (-)-9-Hydroxyrisperidone
Formula:C23H27FN4O3
InChI:InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3/t19-/m0/s1
InChI key:InChIKey=PMXMIIMHBWHSKN-IBGZPJMESA-N
SMILES:FC=1C=C2C(C(=NO2)C3CCN(CCC=4C(=O)N5C(=NC4C)[C@@H](O)CCC5)CC3)=CC1
Synonyms:- R 078544
- 1,2-Benzisoxazole, 4H-pyrido[1,2-a]pyrimidin-4-one deriv.
- (-)-9-Hydroxyrisperidone
- 4H-Pyrido[1,2-a]pyrimidin-4-one, 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-, (9S)-
- (9S)-3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
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Found 5 products.
Risperidone EP Impurity C ((S)-Isomer)-d4 ((S)-9-Hydroxy Risperidone-d4, (S)-Paliperidone-d4)
CAS:Formula:C23H23D4FN4O3Color and Shape:Pale Yellow SolidMolecular weight:430.52(-)-9-Hydroxyrisperidone
CAS:Controlled Product(-)-9-Hydroxyrisperidone is a metabolite of risperidone that is structurally related to the neurotransmitter dopamine. This compound has been found to be a potent antagonist of serotonin and adrenergic receptors, which may contribute to its therapeutic effects in schizophrenia. (-)-9-Hydroxyrisperidone also has been shown to have a high affinity for human liver plasma proteins, which suggests it may be responsible for the long half-life seen with risperidone. The (+) form of the drug has been shown to be more potent than (-)-9-hydroxyrisperidone, while (-)-9-hydroxyrisperidone is more selective in terms of receptor binding.Formula:C23H27FN4O3Purity:Min. 95%Color and Shape:PowderMolecular weight:426.48 g/mol(S)-9-Hydroxy Risperidone
CAS:Controlled ProductApplications The S-enantiomer metabolite of Risperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),Formula:C23H27FN4O3Color and Shape:NeatMolecular weight:426.48Risperidone EP Impurity C ((S)-Isomer) ((S)-9-Hydroxy Risperidone, (S)-Paliperidone)
CAS:Formula:C23H27FN4O3Color and Shape:White To Off-White SolidMolecular weight:426.49
