CAS 14790-42-2: 4-chloro-2-phenylpyrimidine

4-Chloro-2-phenyl-pyrimidine is a synthetic compound that has been shown to be effective against bacterial strains resistant to other antibiotics. 4CPP is an amide with a chloro group at the 2 position and a pyridine ring at the 4 position. It has been shown to inhibit bacteria by binding to the molecule and preventing its function. This binding causes cell death by inhibiting protein synthesis and DNA replication. 4CPP also undergoes phototransformation when exposed to ultraviolet light, which may lead to increased efficacy of this drug in vivo.4CPP is synthesized from 2,4-dichloropyrimidine, which reacts with an amine in acidic conditions. The substituent effects on the aromatic rings are important for determining reactivity of this molecule.END>>

4-Chloro-2-phenylpyrimidine