CAS 1481-27-2: 1-(4-Fluoro-2-hydroxyphenyl)ethanone

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4'-Fluoro-2'-hydroxyacetophenone

4'-Fluoro-2'-hydroxyacetophenone is a chemical that is used as an antibacterial agent. It inhibits the growth of bacteria by interfering with microbial metabolism and inhibiting the synthesis of proteins, DNA, RNA and cell wall components. 4'-Fluoro-2'-hydroxyacetophenone has been shown to be active against P. aeruginosa, Enterococci and other bacterial strains. The compound also reduces the number of viable cells in culture supernatants from these bacteria. The mechanism of action of 4'-fluoro-2'-hydroxyacetophenone is not known but may be related to its ability to form covalent bonds with carbonyl groups present in enzymes or protein structures. The compound can also spontaneously combust when heated to decomposition. This combustion releases fluorine gas which could cause environmental pollution if released into the atmosphere during its manufacture or use.