CAS 148244-82-0: Seco-isolariciresinol diglucoside

Secoisolariciresinol diglucoside is a plant lignan, which is primarily sourced from flaxseed. As a type of phytoestrogen, SDG is known for its antioxidant properties and ability to influence estrogen metabolism. The mode of action involves the conversion of SDG into mammalian lignans such as enterolactone and enterodiol by intestinal microflora, which then exhibit biological activity. These metabolites can bind to estrogen receptors, thereby exerting weak estrogenic or antiestrogenic effects depending on endogenous estrogen levels. The uses and applications of Secoisolariciresinol diglucoside are varied, primarily focusing on its potential health benefits. Its antioxidant activity is being studied for possible roles in the prevention of oxidative stress-related diseases. The phytoestrogenic activity of SDG has garnered interest for its effects on hormone-dependent conditions, such as menopausal symptoms and potentially in hormone-related cancer prevention. Current research also explores its impact on cardiovascular health, metabolic syndrome, and immune function. Despite these promising areas, it is essential to approach findings with scientific rigor, and further studies are necessary to substantiate these potential health benefits fully.

Secoisolariciresinol diglucoside