The chemical substance known as (3E)-3-[(2,4-Dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3′-bipyridine, with the CAS number 148372-04-7, is characterized by its complex molecular structure, which includes a bipyridine core and a dimethoxyphenyl substituent. This compound features a tetrahydro configuration, indicating the presence of a saturated ring system, which contributes to its potential biological activity. The dimethoxy groups on the phenyl ring enhance its lipophilicity and may influence its interaction with biological targets. The E configuration at the 3-position suggests a specific geometric arrangement that can affect the compound's reactivity and binding properties. Such compounds are often studied for their pharmacological potential, particularly in the fields of medicinal chemistry and drug development. Additionally, the presence of multiple functional groups may provide sites for further chemical modification, making it a versatile candidate for research in various applications, including but not limited to, neuropharmacology and organic synthesis.

(3E)-3-[(2,4-Dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3′-bipyridine

148372-04-7: 2,4-Dimethoxybenzylidene anabaseine, (3E)-3-[(2,4-Dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3′-bipyridine, 2,3′-Bipyridine, 3-[(2,4-dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-, (E)-, 2,3′-Bipyridine, 3-[(2,4-dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-, (3E)-

Agonist of α7-nicotinic acetylcholine receptor

GTS 21

GTS-21 (DMXB-A) is an α7 nAChR agonist. GTS-21 suppresses inflammation associated with rheumatoid arthritis by inhibiting RA Th1 cell differentiation.

CAS 148372-04-7: (3E)-3-[(2,4-Dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3′-bipyridine

GTS 21

Ref: 3D-FG43152

GTS-21

Ref: TM-T19933