CAS: 14892-97-8

Scr7 Pyrazine

SCR7 pyrazine

SCR7 pyrazine is a synthetic, catalytic subunit that belongs to the group of protein complexes. It has been shown to have a homologous structure with human DNA polymerase beta, which is involved in transcriptional regulation and DNA replication. SCR7 pyrazine is not efficient in its function, but it has shown an increase in fibroblast proliferation and a shift in the cell cycle from G2/M to S phase. This can be seen by the increased levels of RNA synthesis and DNA replication. SCR7 pyrazine also inhibits the expression of genes involved in apoptosis and cell death. This drug may be used as a potential cancer treatment due to its ability to inhibit proteins involved in apoptosis.

SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).