CAS 148927-23-5: 3-Quinolinecarboxylicacid,6-amino-1-cyclopropyl-7-(3,4-dihydro-2(1H)-isoquinolinyl)-1,4-dihydro-8-methyl-4-oxo-

MF 5137 is an effective antimicrobial agent.

6-Amino-1-cyclopropyl-7-(3,4-dihydro-1H-isoquinolin-2-yl)-8-methyl-4-oxoquinoline-3-carboxylic acid is a synthetic quinolone antibiotic, which is derived from chemical synthesis processes designed to mimic the naturally occurring quinolone core structure. With a specific mechanism of action, it inhibits bacterial DNA gyrase and topoisomerase IV. These enzymes are critical for supercoiling and uncoiling DNA, meaning that their inhibition results in an inability of bacterial cells to properly replicate their DNA, ultimately leading to cell death. This compound is primarily applied in areas where bacterial infections need targeted and effective treatments, especially for Gram-positive and Gram-negative bacteria. Its application is significant in the context of treating resistant bacterial strains that fail to respond to other classes of antibiotics. This makes it invaluable in clinical settings where robust and reliable antibiotic options are paramount. Additionally, its unique structure and action provide utility in research contexts investigating antibiotic resistance mechanisms and developing new antibacterials.