CAS 149-91-7: Gallic acid

Carboxylic acid with phenol function

Gallic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Organic acid is used as a standard for determining phenols in the Folin-Ciocalteau assay3,4,5-Trihydroxybenzoic acid is used as a cyclooxygease inhibitor substance, which is found in plants. In analytical chemistry, it is used as a standard to determine phenol content in various analytes. It acts as a starting material for the preparation of psychedelic alkaloid mescaline. Further, it is used to produce polyesters based on phloretic acid and gallic acid. In addition to this, it is used in the preparation of its esters such as methyl gallate, ethyl gallate, propyl gallate, octyl gallate and doceyl gallate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications Gallic Acid exhibits a number of cellular effects including apoptosis and inhibits the growth of calf pulmonary arterial endothelial cell (CPAEC);Also, it is a polyphenol widely found in numerous fruits and vegetables that has been reported to exert anticancer effects, including apoptosis, against cancer cell lines. References Park, W. H.: Mol. Med. Rep., 16, 7805-7812 (2017); Yang, C., et al.: RSC Adv., 8, 12449-12458 (2018)

3,4,5-Trihydroxybenzoic acid, anhydrous

Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Gallic acid

Gallic acid anhydrous is a compound that is found in plants and has antioxidant properties. Gallic acid anhydrous can be used as a model system for the study of electrochemical impedance spectroscopy. It has shown to have anti-cancer activity in vitro, but not in vivo, against squamous carcinoma cells. In addition, gallic acid anhydrous has been shown to inhibit oral pathogens and to scavenge anion radicals. Gallic acid anhydrous may have structural similarities to procyanidin B4, which is important for its antioxidant activity.

Gallic acid and curcumin are natural phenolic compounds, both have cytotoxic activity in relation to their radical modulating activity, induce apoptosis by different mechanisms, and gallic acid produces higher amounts of radicals and more efficiently scavenged the superoxide anion radical.