Beta-D-Arabinofuranosylamine, 2-deoxy-2-fluoro- (9CI), with the CAS number 149624-26-0, is a synthetic nucleoside analog characterized by the presence of a fluorine atom at the 2' position of the sugar moiety. This compound features a beta configuration of the arabinofuranosyl sugar, which is significant for its biological activity and interaction with nucleic acid synthesis pathways. The substitution of a hydroxyl group with a fluorine atom enhances its stability and can influence its ability to act as an antiviral or anticancer agent. The presence of the amine group contributes to its reactivity and potential for forming hydrogen bonds, which may affect its binding affinity to target enzymes or receptors. This compound is of interest in medicinal chemistry for its potential therapeutic applications, particularly in the development of antiviral drugs. Its structural characteristics make it a valuable tool for studying nucleoside metabolism and the mechanisms of action of nucleoside-based therapeutics.

beta-D-Arabinofuranosylamine, 2-deoxy-2-fluoro- (9CI)

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2-Deoxy-2-fluoro-b-D-arabinofuranosylamine (2DF) is a monophosphate nucleoside analog that is chemically modified to form 2DF. The 2DF has shown antiviral, anticancer, and anti-inflammatory activities. It inhibits the proliferation of cancer cells by blocking the synthesis of DNA and RNA, which are necessary for cellular reproduction. This drug also has been shown to have an activator effect on diphosphate nucleotide incorporation into DNA.

CAS 149624-26-0: beta-D-Arabinofuranosylamine, 2-deoxy-2-fluoro- (9CI)

2-Deoxy-2-fluoro-b-D-arabinofuranosylamine

Ref: 3D-ND89208