CAS: 149838-21-1

Pd-85639 is a synthetic small molecule, which is a product of laboratory-derived chemical synthesis. Its structure mimics certain naturally occurring biomolecules that interact with cellular pathways pivotal in the regulation of cell growth and apoptosis. Specifically, Pd-85639 operates by inhibiting specific enzymes and signaling pathways, leading to the disruption of malignant cell proliferation and induction of programmed cell death. The primary applications of Pd-85639 involve research into its efficacy and mechanism of action in targeted cancer therapies. It is utilized in preclinical studies to better understand its potential role as a chemotherapeutic agent, particularly in cancers that exhibit resistance to conventional treatments. By interfering with key cellular processes, Pd-85639 offers insights into novel therapeutic strategies for oncology, making it a valuable tool in the development of new cancer treatment protocols.

PD-85639 blocks Na+ channels in rat brain neurons (75% at 10 min, >95% at 25 min). Binds Nav1.2 with dual-affinity; competes with anesthetics and activators.