2-Chloro-3-methylbenzonitrile is an organic compound characterized by its aromatic structure, which includes a benzene ring substituted with both a chlorine atom and a nitrile group (–C≡N). The presence of the chlorine atom at the 2-position and a methyl group at the 3-position of the benzene ring contributes to its unique chemical properties. This compound is typically a colorless to pale yellow liquid or solid, depending on its purity and temperature. It is known for its moderate polarity due to the electronegative chlorine and the nitrile group, which can influence its solubility in various organic solvents. 2-Chloro-3-methylbenzonitrile is often utilized in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals, due to its reactivity and ability to undergo various chemical transformations. Safety precautions should be taken when handling this compound, as it may pose health risks through inhalation or skin contact. Proper storage and disposal methods are essential to mitigate environmental impact.

2-CHLORO-3-METHYLBENZONITRILE

15013-71-5: Benzonitrile, 2-Chloro-3-Methyl-

2-Chloro-3-methylbenzonitrile

2-Chloro-3-methylbenzonitrile is a metabolite of naphthalene, a chemical substance that can be found in cigarette smoke and vehicle exhaust. This product is used to detect the presence of naphthalene in urine samples. 2-Chloro-3-methylbenzonitrile has been detected in the urine of smokers with an average detection time of 6 hours. The compound undergoes biotransformation before excretion and can be converted into dihydroxylated metabolites. It also undergoes pharmacokinetic optimization through modifications by β-glucuronidase and monohydroxylation by glucuronyl transferases. A study conducted on rats concluded that 2-chloro-3-methylbenzonitrile has no carcinogenic effects.
2CBM has been shown to inhibit the activity of β-glucuronidase and monohydroxylation by glucuronyl transferases which may lead to

CAS 15013-71-5: 2-CHLORO-3-METHYLBENZONITRILE

2-Chloro-3-methylbenzonitrile

Ref: 54-OR345261

2-Chloro-3-methylbenzonitrile

Ref: 3D-FC154547

2-Chloro-3-methylbenzonitrile

Ref: 10-F047090

Benzonitrile, 2-chloro-3-methyl-

Ref: IN-DA001MCN