4-Quinazolinamine, with the CAS number 15018-66-3, is an organic compound characterized by its quinazoline structure, which consists of a fused benzene and pyrimidine ring. This compound typically appears as a crystalline solid and is known for its potential biological activity, particularly in medicinal chemistry. It may exhibit properties such as antimicrobial, anti-inflammatory, or anticancer activities, making it of interest in pharmaceutical research. The presence of the amino group at the 4-position of the quinazoline ring contributes to its reactivity and ability to form various derivatives. Additionally, 4-Quinazolinamine is soluble in polar solvents, which can influence its application in various chemical reactions and formulations. Its synthesis often involves cyclization reactions of appropriate precursors, and it can serve as a building block for more complex molecules in drug development. As with many chemical substances, safety and handling precautions are essential due to potential toxicity or reactivity.

4-Quinazolinamine

15018-66-3: 4-Aminoquinazoline, 4-Quinazolinamine, 4-Quinazolineamine, NSC 288012, Quinazoline, 4-amino-, Quinazolin-4-ylamine

Quinazolin-4-ylamine

Quinazolin-4-amine

4-Aminoquinazoline

Quinazolin-4-ylamine is a small molecule with potent antitumor activity. It has been shown to inhibit the growth of colorectal adenocarcinoma cells in vitro and in vivo, as well as epidermal growth factor receptor (EGFR) protein target. This drug also has significant cytotoxicity against other human cancer cell lines, such as MDA-MB-231 breast cancer cells. Quinazolin-4-ylamine selectively inhibits EGFR tyrosine kinase activity in vitro and in humans, but not other protein kinases such as PKA or PKC.

CAS 15018-66-3: 4-Quinazolinamine

Quinazolin-4-ylamine

Ref: IN-DA001ME0

Quinazolin-4-amine

Ref: 54-OR32708

4-Aminoquinazoline

Ref: 10-F036682

Quinazolin-4-ylamine

Ref: 3D-FQ41910