CAS 150322-38-6: 5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one is a pharmaceutical drug with antiplatelet activity. It is synthesized by photolysis of the corresponding nitrile in the presence of a metal catalyst such as rhodium or platinum. The compound has a chromophore that absorbs light at wavelengths between 550 and 600 nm. 5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one is used for the synthesis of prasugrel (Efient), which is an oral antiplatelet agent for the

Applications An inactive metabolite of Prasugrel (P701150). References Sugidachi, A., et al.: Br. J. Pharmacol., 129, 1439 (2000); Takahashi, S., et al.: J. Pharm. Sci., 97, 5434 (2008); Williams, E., et al.: Drug Metab. Dispos., 36, 1227 (2008); Hagihara, K., et al.: Xenobiotica, 39, 218 (2009);