CAS: 150972-72-8

7,8-Didehydrocimigenol is a bioactive compound, which is an isoflavone derived primarily from the roots of Cimicifuga species, often known as black cohosh. These plants are indigenous to North America and are well-recognized for their complex mixtures of phytochemicals. The mode of action of 7,8-Didehydrocimigenol involves interaction with estrogen receptors, potentially modulating pathways influenced by these receptors, contributing to its phytoestrogenic activity. This could have implications for menopausal symptom relief, given its ability to mimic or modulate the effects of estrogen in the body. Additionally, 7,8-Didehydrocimigenol is of interest for its potential anti-inflammatory and antioxidant properties, which are beneficial for exploratory studies in reducing oxidative stress and inflammation-related disorders. Its applications span pharmacological research, specifically in studies targeting hormonal regulation, bone density maintenance, and possibly cancer prevention mechanisms. As such, 7,8-Didehydrocimigenol serves as a significant subject of investigation in natural product chemistry and molecular biology, advancing our understanding of plant-derived compounds in human health.

7,8-Didehydrocimigenol treats cardiovascular issues by upregulating PPAR-γ, inhibiting NF-kB, and reducing VCAM-1 in EC.