L-701,252, with the CAS number 151057-13-5, is a chemical compound that belongs to the class of selective serotonin reuptake inhibitors (SSRIs). It is primarily studied for its potential applications in the treatment of various psychiatric disorders, particularly depression and anxiety. The compound exhibits a high affinity for serotonin receptors, which plays a crucial role in modulating mood and emotional responses. L-701,252 is characterized by its ability to selectively inhibit the reuptake of serotonin in the synaptic cleft, thereby increasing its availability and enhancing neurotransmission. This mechanism of action is fundamental to its therapeutic effects. Additionally, L-701,252 has been investigated for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, which are essential for determining its efficacy and safety profile in clinical settings. As with many compounds in this category, ongoing research aims to better understand its full range of effects, potential side effects, and optimal dosing regimens for therapeutic use.

L-701,252

151057-13-5: 7-Chloro-3-(Cyclopropyl-Carbonyl)-4-Hydroxy-2(1H)-Quinoline, 7-Chloro-3-(Cyclopropylcarbonyl)-4-Hydroxy-2(1H)-Quinolinone, 7-Chloro-3-(Cyclopropylcarbonyl)-4-Hydroxy-2(1H)-Quinoline[L-701, 252], 7-chloro-3-(cyclopropylcarbonyl)-2-hydroxyquinolin-4(1H)-one

L-701252, a potent glycine site NMDA receptor antagonist, exhibits an inhibition concentration (IC50) of 420 nM.

CAS 151057-13-5: L-701,252

L-701252

Ref: TM-T22900

2(1H)-Quinolinone, 7-chloro-3-(cyclopropylcarbonyl)-4-hydroxy-

Ref: IN-DA001N1Q

L-701252

Ref: 54-BUP08384