CAS 15174-69-3: 4-hydroxy-3-methylbenzaldehyde

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

4-Hydroxy-3-methylbenzaldehyde is a fungicidal agent that has been shown to have activity against Cryptococcus neoformans. It inhibits the mitochondrial functions of this fungus, which leads to cell death by disrupting the synthesis of fatty acids and other cellular components. 4-Hydroxy-3-methylbenzaldehyde binds to C. neoformans with high affinity, producing a reaction product that interferes with the organism's ability to produce butyric acid. The molecular modelling of this compound shows that it is a pyrazole ring with two benzyl groups on either side of an aldehyde group. This chemical also inhibits gram-negative bacteria by binding to fatty acids in their outer membrane.

4-Hydroxy-3-methylbenzaldehyde