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CAS 153559-76-3: 6-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]-3-pyridinecarboxylic acid

Formula:C24H29NO2
InChI:InChI=1S/C24H29NO2/c1-15-12-18-19(23(4,5)9-8-22(18,2)3)13-17(15)24(10-11-24)20-7-6-16(14-25-20)21(26)27/h6-7,12-14H,8-11H2,1-5H3,(H,26,27)
InChI key:InChIKey=SLXTWXQUEZSSTJ-UHFFFAOYSA-N
SMILES:CC1=C(C2(CC2)C3=CC=C(C(O)=O)C=N3)C=C4C(=C1)C(C)(C)CCC4(C)C
Synonyms:
  • 3-Pyridinecarboxylic acid, 6-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]-
  • 3-Pyridinecarboxylicacid,6-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-Pentamethyl-2-Nap
  • 6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Cyclopropyl]-Nicotinic Acid (For R&D Only)
  • 6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic Acid
  • 6-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]- 3-Pyridinecarboxylic Acid
  • Agn 192620
  • Alrt 268
  • Cd 3127
  • Hthalenyl)Cyclopropyl)-
  • Lg 100268
  • Lg 268
  • See more synonyms
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Found 3 products.
  • LG100268
    Targetmol
    + Info

    LG100268

    CAS:
    LG100268 is a selective, and oral RXR agonist,inducing transcriptional activation in adipocytes; inhibits keratin 17 increases PD-L1 expression.
    Formula:C24H29NO2
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:363.49

    Ref: TM-T19703

    1mg
    48.00€
    5mg
    90.00€
    10mg
    146.00€
    25mg
    305.00€
    50mg
    498.00€
    100mg
    860.00€
    1mL*10mM (DMSO)
    97.00€
  • LG 100268
    Biosynth
    + Info

    LG 100268

    CAS:
    LG 100268 is a synthetic retinoid that binds to Toll-like receptor 7 (TLR7) and inhibits the production of inflammatory cytokines. LG 100268 has been shown to be a novel TLR7 agonist that decreases the production of pro-inflammatory cytokines, such as IL-1β, IL-6, and TNF-α. This agent also has antiviral activity against HIV and cytotoxic effects on HL60 cells. LG 100268 may be useful for treating squamous cell carcinoma or other cancers in which TLR7 is involved in the pathogenesis. LG 100268 shows minimal toxicity at low doses and could serve as a model system for studying the molecular pathogenesis of cancer.
    Formula:C24H29NO2
    Purity:Min. 95%
    Molecular weight:363.49 g/mol

    Ref: 3D-FL24888

    1g
    6,047.00€
    100mg
    1,694.00€
    250mg
    2,749.00€
    500mg
    3,959.00€
  • LG 100268
    TRC
    + Info

    LG 100268

    Controlled Product
    CAS:
    Applications LG 100268 is a potent RXR agonist for evaluation in the treatment of non-insulin-dependent (type II) diabetes mellitus (NIDDM). References Clyne, C., et al.: J. Biol. Chem., 277, 20591 (2002), Santen, R., et al.: J. Clin. Endocrinol. Metab., 87, 3007 (2002), Falender, A., et al.: Endocrinology, 144, 3598 (2003), Sablin, E., et al.: Mol. Cell., 11, 1575 (2003)
    Formula:C24H29NO2
    Color and Shape:Neat
    Molecular weight:363.49

    Ref: TR-L397650

    5mg
    180.00€
    25mg
    573.00€