CAS 1548-13-6: 4-(Trifluoromethyl)phenyl isocyanate

p-Trifluoromethylphenylisocyanate, 99%

4-(Trifluoromethyl)phenyl isocyanate has been used in the synthesis of fluorescent photoinduced electron transfer (PET) chemosensors and 2-ethyl-6-[(4-trifluoromethylphenylcarbamoyl)hydrazino]-benzo[de]iso-quinoline-1,3-dione, an amidourea-based sensor for anions. It has also been used in the synthesis of 1,8-naphthalimide based colorimetric and fluorescent sensor for anions. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

4-(Trifluoromethyl)phenyl isocyanate

4-(Trifluoromethyl)phenyl isocyanate inhibits the activity of enzymes that catalyze the synthesis or degradation of fatty acids. It has been shown to be effective against bowel disease and may also be used for other inflammatory diseases. 4-(Trifluoromethyl)phenyl isocyanate has been shown to inhibit the activity of diacylglycerol lipase, an enzyme that catalyzes the hydrolysis of diacylglycerol to yield glycerol and acetic acid. This inhibition leads to increased levels of diacylglycerol in cells, which may contribute to physiological effects such as inflammation.