CAS 155348-06-4: 1,3-Cyclohexanediol,4-(1-hydroxy-1-methylethyl)-1-methyl-, [1S-(1a,3a,4a)]- (9CI)

p-Menthane-1,3,8-triol is a naturally derived insect repellent, which is a synthetic analog found in small quantities in eucalyptus leaves. Its mode of action involves disrupting the olfactory senses of insects, specifically targeting the chemoreceptors that detect human sweat and breath. This interference reduces the insects’ ability to locate and land on human skin, providing an effective deterrence against mosquito bites. p-Menthane-1,3,8-triol is primarily used in personal care products such as lotions and sprays to prevent mosquito-borne diseases. It is an alternative to the widely used chemical repellent DEET, offering a more natural option with a lower risk of skin irritation. The compound’s efficacy against various mosquito species makes it valuable for use in both endemic regions and areas with seasonal mosquito activity. Its application extends to environmental protection and public health, contributing significantly to global efforts in controlling mosquito populations and minimizing disease transmission.