CAS 155558-32-0: HYDROXYFASUDIL MONOHYDROCHLORIDE
Formula:C14H18ClN3O3S
Synonyms:- 5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-1(2H)-isoquinolinone
- Hydroxyfasudil Hydrochloride
- 1-(1-Hydroxy-5-Isoquinolinesulfonyl)Homopiperazine Monohydrochloride
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Found 7 products.
1(2H)-Isoquinolinone, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1)
CAS:Formula:C14H18ClN3O3SPurity:98%Color and Shape:SolidMolecular weight:343.829Hydroxyfasudil Hydrochloride
CAS:Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).Formula:C14H18ClN3O3SPurity:99.82%Color and Shape:SolidMolecular weight:343.83Hydroxy Fasudil Hydrochloride
CAS:Controlled ProductApplications A metabolite of Fasudil. A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties. Reported to inhibit the Rho kinase-mediated (ROCK) contraction both in vitro and in vivo. References Shimokawa, H., et al.: Cardiovasc. Res., 43, 1029 (1999), Takemoto, M., et al.: Circulation, 106, 57 (2002), Ito, K., et al.: J. Physiol., 546, 823 (2003),Formula:C14H17N3O3S·ClHColor and Shape:NeatMolecular weight:343.83Hydroxyfasudil Hydrochloride
CAS:Formula:C14H17N3O3S·HClPurity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:343.83Hydroxyfasudil hydrochloride
CAS:Hydroxyfasudil hydrochloride is a drug that is used in the treatment of ophthalmic diseases such as choroidal neovascularization and age-related macular degeneration. It is a small molecule that blocks the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) signaling pathway. This prevents the production of inflammatory mediators, which can cause or worsen autoimmune diseases. Hydroxyfasudil hydrochloride has been shown to be safe for use in healthy Chinese populations and has not been found to affect cardiac glycosides or enteric bacterial flora. The drug also has no toxicological effects on animal studies.Formula:C14H18ClN3O3SPurity:Min. 95%Molecular weight:343.83 g/molRef: 3D-FH24355
Discontinued product
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