Tris(trimethylsilyl)phosphine, with the CAS number 15573-38-3, is an organophosphorus compound characterized by its three trimethylsilyl groups attached to a phosphorus atom. This compound is typically a colorless to pale yellow liquid and is known for its stability and low reactivity under ambient conditions. It exhibits properties typical of phosphines, such as being a good ligand in coordination chemistry, and can participate in various chemical reactions, including those involving nucleophilic substitution. The presence of trimethylsilyl groups enhances its solubility in organic solvents and provides steric hindrance, which can influence its reactivity. Tris(trimethylsilyl)phosphine is often utilized in organic synthesis and as a reagent in the preparation of other phosphorus-containing compounds. Additionally, it can serve as a reducing agent and is valuable in the field of organometallic chemistry. Safety precautions should be observed when handling this compound, as it may pose health risks if ingested or inhaled.

Tris(trimethylsilyl)phosphine

15573-38-3: 1,1,1,3,3,3-Hexamethyl-2-(Trimethylsilyl)Disilaphosphane, NSC 117328, Phosphine, tris(trimethylsilyl)-, Tri(trimethylsilyl)phosphine, Tris(trimethylsilyl)phosphane, [Ttris(Trimethylsilyl)]Phosphine, Tris(trimethylsilyl)phosphine

Tris(trimethylsilyl)-phosphine is a non-coordinating reagent that is used to prepare reactive phosphorus compounds. It reacts with fatty acids, such as stearic acid, to produce phospholipids in the presence of a base. Tris(trimethylsilyl)-phosphine also reacts with chloromethylated polyethers and halides to form chloromethylated polyether phosphines. This reaction has been studied extensively using synthetic and natural fatty acids and chlorinated polyethers. Tris(trimethylsilyl)-phosphine is activated by diphenyl ether, which increases its reactivity. The activation energy for this reaction is found to be -26 kJ/mol.

CAS 15573-38-3: Tris(trimethylsilyl)phosphine

Tris(trimethylsilyl)-phosphine

Ref: 3D-FT165404

Tris(trimethylsilyl)phosphine, min. 98% (10 wt% in hexanes)

Ref: 08-15-8021

Tris(trimethylsilyl)phosphine, min. 98%

Ref: 08-15-8020

Tris(trimethylsilyl)phosphine (ca. 10% in Hexane)

Ref: 3B-T3453

Phosphine, tris(trimethylsilyl)-

Ref: IN-DA001O5R