CAS 1566-81-0: 2-[3-[3-(Trifluoromethyl)phenyl]ureido]benzoic acid

NS1652

NS1652 is an anion conductance inhibitor. NS1652 blocks chloride channel has an IC50 of 1.6 μM in human and mouse red blood cells.

NS1652 is a new drug that has been shown to have high potential for interactions with other drugs. It is a cationic amino acid that binds to the red cell membrane and alters transport properties of the cell. NS1652 has been shown to inhibit uptake of the amino acid L-lysine by cells. It also inhibits transfection experiments in vitro, which may be due to its ability to interfere with cellular physiology. NS1652 is a high-resistance, non-selective cation channel blocker that has been shown to have chemical structures similar to those found in common drugs such as ibuprofen, naproxen, indomethacin, and diclofenac. These similarities suggest that it could cause adverse effects when taken with these medications because there would be an increased risk of interaction between the two drugs.