1H-Benzimidazole, 5-nitro-2-phenyl- is an organic compound characterized by its benzimidazole core, which consists of a fused benzene and imidazole ring. The presence of a nitro group at the 5-position and a phenyl group at the 2-position contributes to its chemical reactivity and properties. This compound typically exhibits a yellow to orange color due to the nitro substitution, which can also influence its solubility in various solvents. It is known for its potential applications in pharmaceuticals and as a building block in organic synthesis. The nitro group can participate in electrophilic aromatic substitution reactions, while the benzimidazole moiety is often associated with biological activity, including antimicrobial and antifungal properties. Additionally, the compound may exhibit fluorescence, making it useful in certain analytical applications. Safety data should be consulted, as nitro compounds can be hazardous, and appropriate handling and disposal measures are essential in laboratory settings.

1H-Benzimidazole, 5-nitro-2-phenyl-

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6-NITRO-2-PHENYL-1H-BENZO[D]IMIDAZOLE is a molecule that has been shown to inhibit the activity of topoisomerase, an enzyme involved in DNA replication. 6-NITRO-2-PHENYL-1H-BENZO[D]IMIDAZOLE inhibits the synthesis and release of proinflammatory cytokines and inflammatory molecules, such as prostaglandin E2 (PGE2) and nitric oxide (NO). The inhibition of these molecules is mediated by the inhibition of topoisomerase. This inhibition may be due to its ability to act as a radical. 6NITRO-2-PHENYL-1H-BENZO[D]IMIDAZOLE also inhibits P38 kinase activation in response to stimulation with naphthalene or dithionite.

CAS 1571-85-3: 1H-Benzimidazole, 5-nitro-2-phenyl-

6-NITRO-2-PHENYL-1H-BENZO[D]IMIDAZOLE

Ref: 3D-FN75206

6-Nitro-2-phenyl-1H-benzo[d]imidazole

Ref: 54-OR91295

1H-BENZIMIDAZOLE, 6-NITRO-2-PHENYL-

Ref: IN-DA001P8I

6-NITRO-2-PHENYL-1H-BENZO[D]IMIDAZOLE

Ref: 10-F301219