CAS 15717-45-0: Guanosine, 8-bromo-, 2′,3′,5′-triacetate
Formula:C16H18BrN5O8
InChI:InChI=1S/C16H18BrN5O8/c1-5(23)27-4-8-10(28-6(2)24)11(29-7(3)25)14(30-8)22-12-9(19-15(22)17)13(26)21-16(18)20-12/h8,10-11,14H,4H2,1-3H3,(H3,18,20,21,26)/t8-,10-,11-,14-/m1/s1
InChI key:InChIKey=JLZCAXCVNVVXJL-IDTAVKCVSA-N
SMILES:BrC=1N(C2=C(N1)C(=O)N=C(N)N2)[C@H]3[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O3
Synonyms:- 2',3',5'-tri-O-acetyl-8-bromoguanosine
- 2-amino-8-bromo-9-(2,3,5-tri-O-acetylpentofuranosyl)-3,9-dihydro-6H-purin-6-one
- 2′,3′,5′-Tri-O-acetyl-8-bromoguanosine
- 8-Bromo-2′,3′,5′-tri-O-acetylguanosine
- 8-Bromoguanosine 2',3',5'-triacetate
- 8-Bromoguanosine 2′,3′,5′-triacetate
- Guanosine, 8-bromo-, 2′,3′,5′-triacetate
- NSC 174056
- NSC 79210
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Found 5 products.
8-Bromo-2’,3’,5’-tri-O-acetylguanosine
CAS:Controlled ProductApplications 8-Bromo-2’,3’,5’-tri-O-acetylguanosine (cas# 15717-45-0) is a compound useful in organic synthesis. References Kazmers, I.S., et al.: Science, 214, 1137 (1981), Chern, J-W., et al.: J. Med. Chem., 36, 1024 (1993)Formula:C16H18BrN5O8Color and Shape:NeatMolecular weight:488.25Guanosine, 8-bromo-, 2',3',5'-triacetate
CAS:Formula:C16H18BrN5O8Purity:95%Color and Shape:SolidMolecular weight:488.24688-Bromo-2’,3’,5’-tri-O-acetylguanosine-13C2,15N
CAS:Controlled ProductApplications 8-Bromo-2’,3’,5’-tri-O-acetylguanosine-13C2,15N is an intermediate in the synthesis of 8-Aminoguanosine-13C2,15N (A609877). 8-Aminoguanosine-13C2,15N is an isotopic labelled compound of 8-Aminoguanosine (A609875), which is a potent inhibitor of purine nucleoside phosphorylase. 8-Bromo-2’,3’,5’-tri-O-acetylguanosine-13C2,15N is also a labelled analog of 8-Bromo-2’,3’,5’-tri-O-acetylguanosine (B688325). References Kazmers, I.S., et al.: Science, 214, 1137 (1981); Chern, J-W., et al.: J. Med. Chem., 36, 1024 (1993)Formula:C2C14H18Br15NN4O8Color and Shape:NeatMolecular weight:491.2262',3',5'-Tri-O-acetyl-8-bromoguanosine
CAS:2',3',5'-Tri-O-acetyl-8-bromoguanosine is a synthetic nucleoside analog that inhibits the growth of tumor cells. It has been shown to inhibit the progression of prostate cancer and cervical cancer by binding to guanosine, preventing its conversion into ATP. This compound also prevents proliferation in hek293 and glioblastoma cells. The mechanism of action may be due to oxidative phosphite formation, which causes DNA damage and subsequent apoptosis.Formula:C16H18BrN5O8Purity:Min. 95%Color and Shape:Off-White To Light (Or Pale) Yellow SolidMolecular weight:488.25 g/mol
